CYCLONE NATION · BIG 12 · 2026 SEASON

Iowa State Cyclones Football

Everything Iowa State football: schedule, scores, roster, stats, odds, history, head-to-head series, game day info and matchup simulator.

vs Southeast Missouri State
Jack Trice Stadium
3
DAYS
16
HRS
33
MIN

Southeast Missouri State vs Iowa StateSEMO vs ISU · Week 1

How to Watch →

Iowa State opens the 2026 season against Southeast Missouri State on Saturday, Sep 5 at Jack Trice Stadium.

TVTBD
StreamingESPN+

SEASON

Overall0–0
Big 120–0

CFB VIBES MODEL

10,000 simulations10K sims

The Read

Iowa State opens a 29.5-point favorite. Our model gives Iowa State a 97% chance.

WIN PROBABILITY
ISU 97% SEMO 3%
PROJECTED FINAL
Southeast Missouri State
13
ISU win
97%
One-score game
8%

What's driving the model

Home-field edge ISU
Market lean ISU
Model projection ISU
Each game samples a margin around the market spread and a final total around the market total.
Southeast Missouri St @ Iowa St

Your sims:Sims: ISU 0, SEMO 0

SEMO@
Southeast Missouri St @ Iowa St
CFB VIBES MODELISU 97% to win
@#22
Iowa State @ Iowa
CFB VIBES MODELIOWA 77% to win
@
Bowling Green @ Iowa State
CFB VIBES MODELISU 87% to win
#21@
Utah @ Iowa State
TBD
CFB VIBES MODELUTAH 64% to win
PlaceTEAMCONFOVERALL
8CincinnatiCIN0–00–0
9ColoradoCOLO0–00–0
10Iowa StateISU0–00–0
11KansasKU0–00–0
12Kansas StateKSU0–00–0

PREDICTION MARKETS & ODDSMARKET & ODDS

All odds →All →

THE LINE

SpreadISU −29.5
Total53.5