Louisville vs Southern Illinois Series
Louisville leads the series with Southern Illinois 7–3 across 10 meetings.
| MEETINGS | 10 |
| SERIES | Louisville leads 7–3 |
| LOUISVILLE WINS | 7 |
| SOUTHERN ILLINOIS WINS | 3 |
| STREAK | Louisville won the last 2 |
| LAST MEETING | Louisville 20, Southern Illinois 16 · 1972 |
| FIRST ON RECORD | Southern Illinois 13, Louisville 7 · 1963 |
EVERY MEETING
10 MEETINGS · 1963–1972
| SEASON | DATE | RESULT | LOCATION |
|---|---|---|---|
| 1972 | Nov 11, 1972 | Louisville 20, Southern Illinois 16 | – |
| 1971 | Nov 13, 1971 | Louisville 24, Southern Illinois 14 | – |
| 1970 | Sep 19, 1970 | Southern Illinois 31, Louisville 28 | – |
| 1969 | Sep 20, 1969 | Louisville 17, Southern Illinois 13 | – |
| 1968 | Sep 21, 1968 | Louisville 33, Southern Illinois 10 | – |
| 1967 | Sep 23, 1967 | Louisville 26, Southern Illinois 0 | – |
| 1966 | Sep 24, 1966 | Louisville 16, Southern Illinois 7 | – |
| 1965 | Sep 25, 1965 | Louisville 13, Southern Illinois 0 | – |
| 1964 | Sep 26, 1964 | Southern Illinois 7, Louisville 6 | – |
| 1963 | Oct 5, 1963 | Southern Illinois 13, Louisville 7 | – |