Mississippi Valley State vs Southern Series
Southern leads the series with Mississippi Valley State 11–1 across 12 meetings.
| MEETINGS | 12 |
| SERIES | Southern leads 11–1 |
| MISSISSIPPI VALLEY STATE WINS | 1 |
| SOUTHERN WINS | 11 |
| STREAK | Southern won the last 7 |
| LAST MEETING | Southern 34, Mississippi Valley State 29 · 2025 |
| FIRST ON RECORD | Southern 23, Mississippi Valley State 6 · 2007 |
