| 2024 | Sep 21, 2024 | Buffalo 23, Northern Illinois 20 (OT) (OT) | Huskie Stadium · DeKalb, IL |
| 2021 | Nov 17, 2021 | Northern Illinois 33, Buffalo 27 (OT) (OT) | UB Stadium · Amherst, NY |
| 2020 | Nov 4, 2020 | Buffalo 49, Northern Illinois 30 | Huskie Stadium · DeKalb, IL |
| 2018 | Nov 30, 2018 | Northern Illinois 30, Buffalo 29 | Ford Field · Detroit, MI · Neutral |
| 2017 | Oct 14, 2017 | Northern Illinois 14, Buffalo 13 | UB Stadium · Amherst, NY |
| 2016 | Oct 22, 2016 | Northern Illinois 44, Buffalo 7 | Huskie Stadium · DeKalb, IL |
| 2015 | Nov 11, 2015 | Northern Illinois 41, Buffalo 30 | UB Stadium · Amherst, NY |
| 2012 | Oct 13, 2012 | Northern Illinois 45, Buffalo 3 | Huskie Stadium · DeKalb, IL |
| 2011 | Oct 22, 2011 | Northern Illinois 31, Buffalo 30 | UB Stadium · Amherst, NY |
| 2010 | Oct 16, 2010 | Northern Illinois 45, Buffalo 14 | Huskie Stadium · DeKalb, IL |
| 2006 | Sep 16, 2006 | Northern Illinois 31, Buffalo 13 | Huskie Stadium · DeKalb, IL |
| 2003 | Nov 8, 2003 | Northern Illinois 40, Buffalo 9 | UB Stadium · Amherst, NY |
| 2000 | Oct 28, 2000 | Northern Illinois 73, Buffalo 10 | – |
| 1999 | Oct 2, 1999 | Northern Illinois 45, Buffalo 21 | – |
| 1970 | Nov 21, 1970 | Northern Illinois 43, Buffalo 26 | – |
| 1968 | Nov 9, 1968 | Buffalo 20, Northern Illinois 7 | – |
VS
