| 2026 | Oct 24, 2026 | Southeast Missouri State 20, Eastern Illinois 10 | O'Brien Stadium · Charleston, IL |
| 2025 | Oct 18, 2025 | Southeast Missouri State 42, Eastern Illinois 13 | Houck Field · Cape Girardeau, MO |
| 2024 | Oct 5, 2024 | Southeast Missouri State 38, Eastern Illinois 27 | O'Brien Stadium · Charleston, IL |
| 2023 | Oct 14, 2023 | Southeast Missouri State 35, Eastern Illinois 28 | Houck Field · Cape Girardeau, MO |
| 2022 | Nov 12, 2022 | Southeast Missouri State 31, Eastern Illinois 7 | O'Brien Stadium · Charleston, IL |
| 2021 | Oct 30, 2021 | Southeast Missouri State 38, Eastern Illinois 15 | Houck Field · Cape Girardeau, MO |
| 2020 | Feb 28, 2021 | Southeast Missouri State 47, Eastern Illinois 7 | O'Brien Stadium · Charleston, IL |
| 2019 | Nov 16, 2019 | Southeast Missouri State 26, Eastern Illinois 12 | O'Brien Stadium · Charleston, IL |
| 2018 | Nov 17, 2018 | Southeast Missouri State 38, Eastern Illinois 32 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2017 | Sep 23, 2017 | Eastern Illinois 19, Southeast Missouri State 16 | O'Brien Stadium · Charleston, IL |
| 2016 | Oct 1, 2016 | Southeast Missouri State 21, Eastern Illinois 14 | Houck Stadium · Cape Girardeau, MO |
| 2015 | Oct 10, 2015 | Eastern Illinois 33, Southeast Missouri State 28 | O'Brien Stadium · Charleston, IL |
| 2014 | Oct 18, 2014 | Eastern Illinois 52, Southeast Missouri State 13 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2012 | Nov 10, 2012 | Eastern Illinois 39, Southeast Missouri State 20 | O'Brien Stadium · Charleston, IL |
| 2011 | Oct 1, 2011 | Southeast Missouri State 37, Eastern Illinois 30 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2010 | Oct 2, 2010 | Southeast Missouri State 28, Eastern Illinois 13 | O'Brien Stadium · Charleston, IL |
| 2009 | Sep 19, 2009 | Eastern Illinois 23, Southeast Missouri State 14 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2008 | Oct 18, 2008 | Eastern Illinois 24, Southeast Missouri State 21 | O'Brien Stadium · Charleston, IL |
| 2007 | Sep 29, 2007 | Eastern Illinois 31, Southeast Missouri State 16 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2006 | Oct 7, 2006 | Eastern Illinois 21, Southeast Missouri State 0 | O'Brien Stadium · Charleston, IL |
| 2005 | Oct 8, 2005 | Eastern Illinois 48, Southeast Missouri State 24 | Houck Stadium · Cape Girardeau, MO · Neutral |
| 2004 | Oct 2, 2004 | Eastern Illinois 35, Southeast Missouri State 28 | O'Brien Stadium · Charleston, IL |
| 2003 | Oct 4, 2003 | Southeast Missouri State 30, Eastern Illinois 17 | Houck Stadium · Cape Girardeau, MO · Neutral |
