Indiana State vs Southern Illinois Series
Southern Illinois leads the series with Indiana State 15–6 across 21 meetings.
| MEETINGS | 21 |
| SERIES | Southern Illinois leads 15–6 |
| INDIANA STATE WINS | 6 |
| SOUTHERN ILLINOIS WINS | 15 |
| STREAK | Southern Illinois won the last meeting |
| LAST MEETING | Southern Illinois 55, Indiana State 27 · 2025 |
| FIRST ON RECORD | Southern Illinois 37, Indiana State 14 · 2003 |
