Southern Illinois vs Youngstown State Series
Youngstown State leads the series with Southern Illinois 12–11 across 23 meetings.
| MEETINGS | 23 |
| SERIES | Youngstown State leads 12–11 |
| SOUTHERN ILLINOIS WINS | 11 |
| YOUNGSTOWN STATE WINS | 12 |
| STREAK | Youngstown State won the last meeting |
| LAST MEETING | Youngstown State 48, Southern Illinois 38 · 2025 |
| FIRST ON RECORD | Southern Illinois 24, Youngstown State 17 · 2003 |
